Dr. Safdar Hussain

4. Ayyaz, Muhammad; Sarfraz, Muhammad; Arshad, Muhammad; Yaqoob, Asma; Siddique, Sabir Ali; Hussain, Safdar; Ali, Muhammad Arif; Qureshi, Ashfaq Mahmood; Rauf, Abdul;. 2024. “Design, synthesis, in-vitro biological screening and in-silico studies of 2-thioxodihydropyrimidinone based new aminomethylene scaffolds.” Journal of Molecular Structure 1299. DOI: 10.1016/j.molstruc.2023.137153

5. Abdullah, Shawana; Iqbal, Ambar; Ashok, Avinash Karkada; Kaouche, Farah Chafika; Aslam, Misbah; Hussain, Safdar; Rahman, Jameel; Hayat, Muhammad Munawar; Ashraf, Muhammad;. 2024. “Anti-enzymatic and DNA docking studies of montelukast: A multifaceted molecular scaffold with in vitro investigations, molecular expression analysis and molecular dynamics simulations.” Heliyon 10. DOI: 10.1016/j.heliyon.2024.e24470

6. Naseem, Saira; Khan, Samra; Hussain, Safdar; Mirza, Muhammad Usman; Ashraf, Muhammad; Shafiq, Zahid; Trant, John F;. 2023. “Synthesis, biological evaluation, and molecular docking study of xanthene-linked thiosemicarbazones as cholinesterase inhibitors.” Journal of Biomolecular Structure and Dynamics 42. DOI: 10.1080/07391102.2023.2274981

7. Arfan, Muhammad; Siddiqui, Sabahat Zahra; Abbasi, Muhammad Athar; Saad, Syed Muhammad; Shah, Syed Adnan Ali; Ashraf, Muhammad; Hussain, Safdar; Ali, Farman; Solangi, Mehwish; Khan, Khalid Mohammed;. 2023. “Innovative cholinergic scaffolds, synthesis, and characterization of substituted 1, 2, 4-triazole-3-ylthio-N-acetamides and their in silico studies: supplement against neurodegenerative disease.” Journal of the Iranian Chemical Society 20. DOI: 10.1007/s13738-023-02756-3

8. Chaudhry, Faryal; Munir, Rubina; Ashraf, Muhammad; Huma, Rahila; Malik, Nayab; Hussain, Safdar; Munawar, Munawar Ali; Khan, Misbahul Ain;. 2022. “Exploring facile synthesis and cholinesterase inhibiting potential of heteroaryl substituted imidazole derivatives for the treatment of Alzheimer’s disease.” Arabian Journal of Chemistry 16. DOI: 10.1016/j.arabjc.2022.104384

9. Tariq, Sidra; Mutahir, Sadaf; Khan, Muhammad Asim; Mutahir, Zeeshan; Hussain, Safdar; Ashraf, Muhammad; Bao, Xiaofang; Zhou, Baojing; Stark, Christian BW; Khan, Islam Ullah;. 2022. “Synthesis, in vitro cholinesterase inhibition, molecular docking, DFT, and ADME studies of novel 1, 3, 4?oxadiazole?2?thiol derivatives.” Chemistry & Biodiversity 19. DOI: 10.1002/cbdv.202200157

10. Amjad, Hira; Abbasi, Muhammad Athar; Siddiqui, Sabahat Zahra; Iqbal, Javed; Rasool, Shahid; Ashraf, Muhammad; Hussain, Safdar; Shah, Syed Adnan Ali; Imran, Syahrul; Shahid, Muhammad;. 2022. “In vitro and in silico assessment of bioactivity properties and pharmacokinetic studies of new 3, 5-disubstituted-1, 2, 4-triazoles.” Journal of Molecular Structure 1275. DOI: 10.1016/j.molstruc.2022.134720

11. Javid, Jamila; Abbasi, Muhammad A; Siddiqui, Sabahat Z; Iqbal, Javed; Virk, Naeem A; Rasool, Shahid; Ali, Hira A; Ashraf, Muhammad; Shahid, Wardah; Hussain, Safdar;. 2021. “Comparative conventional and microwave assisted synthesis of heterocyclic oxadiazole analogues having enzymatic inhibition potential.” Journal of Heterocyclic Chemistry 58. DOI: 10.1002/jhet.4150

12. Siddiqui, Sabahat Zahra; Arfan, Muhammad; Abbasi, Muhammad Athar; Shah, Syed Adnan Ali; Ashraf, Muhammad; Hussain, Safdar; Saleem, Rahman Shah Zaib; Rafique, Rafaila; Khan, Khalid Mohammed;. 2020. “Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1, 2, 4?Triazole?3?Thiol: Synthesis and In Silico Molecular Study.” ChemistrySelect 5. DOI: 10.1002/slct.201904905

13. Riaz, Naheed; Iftikhar, Muhammad; Saleem, Muhammad; ur Rehman, Aziz; Ahmed, Ishtiaq; Hussain, Safdar; Ashraf, Muhammad; Nawaz, Zahid; Rahman, Jameel; al Rashida, Mariya;. 2020. “Enzyme Inhibition and In Silico Studies of New Synthetic N-Substituted-(4-Bromophenyl)-4-Ethoxybenzenesulfonamides.” Organic & Medicinal Chemistry International Journal 10. DOI: 10.19080/OMCIJ.2020.10.555783

14. Riaz, Naheed; Iftikhar, Muhammad; Saleem, Muhammad; Hussain, Safdar; Rehmat, Fatima; Afzal, Zainab; Khawar, Saba; Ashraf, Muhammad; al-Rashida, Mariya;. 2020. “New synthetic 1, 2, 4-triazole derivatives: Cholinesterase inhibition and molecular docking studies.” Results in Chemistry 2. DOI: 10.1016/j.rechem.2020.100041

15. Jawaria, Rifat; Hussain, Mazhar; Ahmad, Hafiz Badaruddin; Ashraf, Muhammad; Hussain, Safdar; Naseer, Muhammad Moazzam; Khalid, Muhamamd; Hussain, Muhammad Ajaz; Al-Rashida, Mariya; Tahir, Muhammad Nawaz;. 2020. “Probing ferrocene-based thiosemicarbazones and their transition metal complexes as cholinesterase inhibitors.” Inorganica Chimica Acta 508. DOI: 10.1016/j.ica.2020.119658

16. Ali, Basharat; Khan, Khalid Mohammed; Hussain, Shafqat; Hussain, Safdar; Ashraf, Muhammad; Riaz, Muhammad; Wadood, Abdul; Perveen, Shahnaz;. 2018. “Synthetic nicotinic/isonicotinic thiosemicarbazides: In vitro urease inhibitory activities and molecular docking studies.” Bioorganic chemistry 79. DOI: 10.1016/j.bioorg.2018.04.004

17. Ali, Basharat; Khan, Khalid Mohammed; Salar, Uzma; Hussain, Safdar; Ashraf, Muhammad; Riaz, Muhammad; Wadood, Abdul; Taha, Muhammad; Perveen, Shahnaz;. 2018. “1-[(4?-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as potent urease inhibitors: Synthesis, in vitro and in silico studies.” Bioorganic chemistry 79. DOI: 10.1016/j.bioorg.2018.05.017