Dr. Arslan Sehgal

For his contributions in the field, he was awarded with Research Productivity Award for the year of 2015, 2016 and 2017 by CUI, and CAS-TWAS president fellowship award 2015. Moreover, in 2018, he was honored with the Excellent International Student of UCAS 2018.

Corresponding Author

• Epidemiological studies of sleep disorder in educational community of Pakistani population, its major risk factors and associated diseases.PloS one2022, 17 (4), e0266739 (IF: 3.14)
• Epitope-based peptide vaccine design and elucidation of novel compounds against 3C like protein of SARS-CoV-2. Plos one 2022, 17.3 e0264700 (IF: 3.14)
• Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope-Based Peptide Vaccine and Novel Compounds against Novel SARS-CoV-2 through Virtual Screening. BioMed Research International, 2021, (IF: 3.411)
•  The life cycle and in silico elucidation of non-structural replicating proteins of HCV through a pharmacoinformatics approach. Combinatorial Chemistry & High Throughput Screening, 2021 (IF: 1.339)
• Anti-aging natural compounds and their role in the regulation of metabolic pathways leading to longevity. Mini Reviews in Medicinal Chemistry, 2021, (IF: 3.860)
• Determine the potential Epitope based Peptide Vaccine against novel SARS-CoV-2 targeting structural proteins using immunoinformatics approaches. Frontiers in Molecular Biosciences, 2020, 7, 227 (IF: 5.246)
• In Silico identification of angiotensin-converting enzyme inhibitory peptides from MRJP1. PloS One, 2020, 15 (2), e0228265. (IF: 3.240)
• Ligand-Based Pharmacophore Modeling and Virtual Screening to Discover Novel CYP1A1 Inhibitors. Current Topics in Medicinal Chemistry, 2019, 19 (30), 2782-2794. (IF: 3. 3.295)
• Pharmacoinformatics and molecular docking reveal potential drug candidates against Schizophrenia to target TAAR6. Journal of Cellular Physiology, 2019, 234 (8), 13263-13276. (IF: 6.384)
• Immunoinformatics and molecular docking studies reveal potential Epitope based Peptide Vaccine against DENV-NS3 Protein. Journal of Theoretical Biology, 2018, 459, 162-170. (IF: 2.691)
• Current Therapeutic Molecules and Targets in Neurodegenerative Diseases Based on in silico Drug Design. Current Neuropharmacology, 2018, 16(6), 649-663. (IF: 7.360)
• Pharmacoinformatics and Molecular Docking Studies Reveal Potential Novel Compounds Against Schizophrenia by Target SYN II. Combinatorial Chemistry & High Throughput Screening 2018, 21(3), 175-181. (IF: 1.339)
• Pharmacoinformatics and molecular docking studies reveal potential novel Proline Dehydrogenase (PRODH) compounds for Schizophrenia inhibition. Medicinal Chemistry Research 2017, 26(2), 314-326. (IF: 1.965)
• Pharmacoinformatics, Adaptive Evolution, and Elucidation of Six Novel Compounds for Schizophrenia Treatment by Targeting DAOA (G72) Isoforms. BioMed Research International, 2017,Article ID 5925714, doi:10.1155/2017/5925714. (IF: 3.411)
• Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB. Drug Design Development and Therapy 2016, 10, 1605 (IF: 4.162)
• Comparative Modeling, Molecular Docking, and Revealing of Potential Binding Pockets of RASSF2; a Candidate Cancer Gene. Interdisciplinary Sciences: Computational Life Sciences, 2017, 9(2), 214-223. (IF: 2.233)

Principal Author

• Molecular docking analyses of CYP450 monooxygenases of Tribolium castaneum (Herbst) reveal synergism of quercetin with paraoxon and tetraethyl pyrophosphate: in vivo and in silico studies. Toxicology Research, 2020, tfaa023, https://doi.org/10.1093/toxres/tfaa023. (IF: 3.524)
• Adaptive Evolution and Elucidating the potential inhibitor against Schizophrenia to target DAOA (G72) Isoforms. Drug Design Development and Therapy 2015, 9, 3471 (IF: 4.162)
• Pharmacoinformatics elucidation of potential drug targets against migraine to target ion channel protein KCNK18. Drug Design Development and Therapy 2014 8, 571-581. (IF: 4.162)
• Tumor Necrosis Factor Receptor Superfamily 10B (TNFRSF10B), An insight from structure modeling to virtual screening for designing drug against head and neck cancer. Theoretical Biology and Medical Modeling 2013, 10:38. (IF: 2.432)
• Structural, phylogenetic and docking studies of D-amino acid oxidase activator (DAOA), a candidate schizophrenia gene. Theoretical Biology and Medical Modeling 2013, 10:1. (IF: 2.432)

Co-Author

• The multifaceted regulation of mitophagy by endogenous metabolites. Autophagy, 2021, doi.org/10.1080/15548627.2021.1975914. (IF: 16.016)
• Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy. Redox Biology, 2020, 101661 (IF: 11.799)
• Identification of effective membrane efflux transporters against β‐amyrin through molecular docking approach. Journal of Chemical Technology & Biotechnology, 2019 94 (9), 2869-2875. (IF: 3.174)
• STING directly activates autophagy to tune the innate immune response. Cell Death and Differentiation 2019, 26 (9), 1735-1749 (IF: 15.828)
• Prevalence of Extended Spectrum β-Lactamases in Multi-drug Resistant Pseudomonas aeruginosa from Diabetic Foot Patients. Endocrine, Metabolic & Immune Disorders Drug Targets 2019, 19(4), 443-448 doi.org/10.2174/1871530319666181128095753. (IF: 2.895)
• Formulation and Characterization of a Self-Emulsifying Drug Delivery System (SEDDS) of Curcumin for the Topical Application in Cutaneous and Mucocutaneous Leishmaniasis. Current Topics in Medicinal Chemistry 2018, 18(18), 1603-1609. (IF: 3.295)
• In Silico characterization and In-Vivo validation of Albiziasaponin-A, Iso-Orientin and Salvadorin using a rat model of Alzheimer’s disease. Frontiers in Pharmacology 2018, 9, 730. (IF: 5.810)
• Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis. Journal of Molecular Graphics and Modelling 2017, 74, 296-304 (IF: 2.518)
• Mitochondrial E3 ligase MARCH5 regulates FUNDC1 to fine‐tune hypoxic mitophagy. EMBO reports, 2017, 18(3), 495-509 p.e201643309. (IF: 8.807)
• Mitophagy Receptors Sense Stress Signals and Couple Mitochondrial Dynamic Machinery for Mitochondrial Quality Control. Free Radical Biology and Medicine 2016 100, 199-209. (IF: 7.376)
• Regulatory cascade of neurological loss and glucose metabolism. CNS & Neurological Disorders - Drug Targets 2014 13(7), 1232-1245. (IF: 4.388)

Books             

• Quick Guideline for Computational Drug Design. 2018 Bentham Science Publishers (First and Corresponding author) (ISBN: 978-1-68108-604-0)
• Quick Guideline for Computational Drug Design Revised Edition 2021 Bentham Science Publishers (First and Corresponding author) (ISBN: 978-981-4998-70-3)

Department of Bioinformatics, The Islamia University of Bahawalpur, 63100-Pakistan